Thiol–ene click chemistry: a biocompatible way for orthogonal bioconjugation of colloidal nanoparticles† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01447c Click here for additional data file.
نویسندگان
چکیده
Molecular Science and Biomedicine L Chemo/Bio-Sensing and Chemometrics, Chemistry and Chemical Engineering, A Province, Hunan University, Changsha, Hun ac.cn. Center for Research at Bio/Nano Interface, Physiology and Functional Genomics, Heal McKnight Brain Institute, University of Fl USA. E-mail: [email protected].edu George & Josephine Butler Polymer Researc Science & Engineering, Department of Chem Florida 32611-7200, USA. E-mail: sumerlin@ † Electronic supplementary informa 10.1039/c7sc01447c Cite this: Chem. Sci., 2017, 8, 6182
منابع مشابه
Thiol-ene click chemistry: a biocompatible way for orthogonal bioconjugation of colloidal nanoparticles.
Bioconjugation based on crosslinking primary amines to carboxylic acid groups has found broad applications in protein modification, drug development, and nanomaterial functionalization. However, proteins, which are made up of amino acids, typically give nonselective bioconjugation when using primary amine-based crosslinking. In order to control protein orientation and activity after conjugation...
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